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Southern Brisket Grilled Cheese Recipe


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3.9 from 32 reviews

  • Author: Emma
  • Total Time: 20 minutes
  • Yield: 4 servings 1x
  • Diet: Nut-Free

Description

This Southern Brisket Grilled Cheese combines tender, flavorful BBQ brisket with melted cheddar and mozzarella cheeses between golden, buttery sourdough bread slices. A perfect comfort food sandwich that melds smoky, cheesy, and tangy flavors with optional pickled red onions for a delightful bite.


Ingredients

Scale

Bread and Butter

  • 8 slices thick-cut sourdough or Texas toast bread
  • 2 tablespoons butter, softened

Cheese

  • 1 1/2 cups shredded cheddar cheese
  • 1 1/2 cups shredded mozzarella cheese

Brisket and Sauce

  • 2 cups cooked beef brisket, chopped or shredded
  • 1/4 cup barbecue sauce

Seasonings and Extras

  • 1/4 cup pickled red onions (optional)
  • 1/2 teaspoon garlic powder

Instructions

  1. Prepare the brisket: In a bowl, toss the chopped brisket with barbecue sauce until the meat is well coated, ensuring each bite will be flavorful and juicy.
  2. Season the bread: Butter one side of each bread slice evenly. On the unbuttered side, sprinkle a light layer of garlic powder to add subtle aromatic flavor.
  3. Heat the skillet: Place a skillet or griddle over medium heat, allowing it to warm up for optimal grilling without burning the bread.
  4. Assemble the sandwiches: Place four slices of bread buttered side down on the heated skillet. On each, layer a mixture of cheddar and mozzarella cheeses, followed by a generous portion of the BBQ brisket, and add pickled red onions if using.
  5. Top and grill: Cover each with the remaining bread slices, buttered side facing up. Grill the sandwiches for 3 to 4 minutes per side, pressing down gently with a spatula, until the bread turns golden brown and the cheeses melt thoroughly.
  6. Serve: Remove sandwiches from skillet, slice in half, and serve hot to enjoy the melty, smoky goodness.

Notes

  • Use leftover brisket or store-bought cooked brisket for a speedy preparation.
  • Add jalapeños to the sandwich for a spicy kick.
  • Include a slice of tomato for a fresh Southern twist.
  • Pairs wonderfully with coleslaw or sweet potato fries for a complete meal.
  • Prep Time: 10 minutes
  • Cook Time: 10 minutes
  • Category: Main Course
  • Method: Stovetop
  • Cuisine: Southern American